(Internal Disease - Collagen)

Etiology and pathogenesis are not sufficiently clear. It is assumed that this common infectious-allergic disease associated with the presence in the body the focus of chronic infection (chronic tonsillitis, otitis, cholecystitis, etc.). Continuous flow in the blood of toxins from the infection focus leads to a change in immunological reactivity and the development of allergy. In the process of disorganization of connective tissue (mainly tissue of the joints), released a number of substances purchased properties autoantigens, against which antibodies are formed and the whole process takes autoimmune in nature, manifested by persistent, progressive course. In the blood of pat [more..]

(Internal Disease - Collagen)

Rheumatism or Rheumatic Fever in Children is most often developing due to diffuse myocarditis. The first signs: the deterioration of general condition, fever, pale skin, complaints of feeling unwell, headache, disturbed sleep, appetite, fatigue, discomfort in the heart, shortness of breath. An objective study revealed expansion of the boundaries of the heart, tachycardia, heart rhythm disturbance, the rhythm of “gallop”, systolic sound on top. Electrocardiographic violation intraatrial conduction, prolongation of the interval P-Q, reduction, expansion and splitting of the wave R, reduction of the T wave in all leads. T spike becomes isoelectric, biphasic o [more..]

(Internal Disease - Collagen)

Etiology and pathogenesis. The first attack of rheumatism in most cases connected with the previous haemolytic streptococcal infection, although some patients with streptococcal persuasive communication is not established.

There is strong evidence of the role of allergy and autoallergy in the pathogenesis of rheumatic fever: the proximity of a number of clinical and anatomical manifestations of rheumatic fever and the typical allergic syndromes in the clinic and experiments are often influenced by acute nonspecific factors (”false allergy”), therapeutic effect allergy drugs, the detection of antibodies to the tissues of the joints, skin and internal organs [more..]