(Internal Disease - Circulatory)

Acute reticulosis - a form of acute leukemia characterized by a hyperplastic process involving the reticular tissue of the stroma-forming organs and by aleukemic blood picture, in which the undifferentiated and immature hematopoietic elements do not enter the peripheral blood, or get it in small quantities.

Symptoms and flow. Is rare and occurs usually in the absence of clinical symptoms of hyperplasia of hematopoietic organs, but with rapidly progressive pancytopenia. It is characterized by sudden fever appears to 39-40, severe intoxication, sharp pains in the bones and joints.

According to the clinical picture and the composition of peripheral blood resembles apl [more..]

(Internal Disease - Circulatory)

Hemophilia - a form of hemorrhagic diathesis, in which the tendency to bleeding due to an impaired blood coagulation due to deficiency of plasmic thromboplastin generation.

Etiology and pathogenesis. Hemophilia occurs in the form of congenital, rarely sporadic forms. Hemophiliacs suffer from male carriers of the disease are women.

A-form of Hemophilia associated with the lack anti-hemophilic globulin and occurs in 80-90% of patients with hemophilia.

B-form of Hemophilia is caused by lack of the plasmic thromboplastin component, occurs in 10-15% of patients with hemophilia.

C-form of Hemophilia characterized by lack of plasmic thromboplastin p [more..]

(Internal Disease - Circulatory)

Acute Acquired Hemolytic Anemia

Etiology and pathogenesis. Arise as a result of infections (sepsis, malaria, etc.), intoxications hemolytic poisons (phosphorus, phenylhydrazine, or mushroom, snake venom, etc.), physical factors (cooling, burns). Increased hemolysis arises from the direct effects on red blood cells of the pathogenic factor and as a result of the influence of exogenous factors that lead to the formation of anti-erythrocyte antibodies in the application of certain medicinal substances. Thus, the use of Amidopyrine, Quinine, sulfanilamide and other drugs can lead to the formation of autoantibodies. As a result, connecting them with proteins and blood cells, t [more..]

(Internal Disease - Circulatory)

Thalassemia

Etiology and pathogenesis. The disease is inherited family trait the predominance of red blood cells of fetal embryonic hemoglobin.

Symptoms and flow. There are large, small and minimal thalassemia. The first form of thalassemia in children-homozygotes, the latter two forms a child of heterozygotes. A typical symptom for thalassemia major is a progressive anemia with erythroblastosis, enlarged spleen and liver, osteoporosis, with peculiar changes in bones of the skull (disproportionate proliferation of parietal and occiput) as a consequence of abnormal proliferation of erythroblastic germ in the bone marrow. In the blood, anemia with eritroblasto [more..]

(Internal Disease - Circulatory)

Chronic Posthemorrhagic Anemia is also known as Thalassemia or Cooley’s Anaemia.

Etiology. Arises as a result of repeated bleeding for a long period.

Symptoms and flow is characterized by gradually developing weakness, shortness of breath with movements, heart palpitations, dizziness. Pale skin and visible mucous membranes. The picture of blood to the forefront decline in hemoglobin and red blood cells. As a result of chronic bleeding there is increased loss of body iron stores, which affects a hypochromia of erythrocytes and thus to reduce the color index of blood to 0,6-0,7. Reveals the degenerative forms of erythrocytes: poykilotsity, anizotsity. Th [more..]

(Internal Disease - Circulatory)

Acute posthemorrhagic anemia or acute blood loss anemia - a disease associated with loss of a large volume of hemoglobin.

Etiology. Developed as a result of acute blood loss during injury or disease complicated with hemorrhage.

Symptoms and flow. Actually anemia with concomitant hypoxia, hemodynamic symptoms (collapse). Immediately after bleeding red blood is usually not sharply reduced due to a reflex decrease in total vascular channel and compensatory revenues deposited into the circulation of blood. After 1-2 days, upon receipt of a blood flow of tissue fluid and restore the original volume of the vascular channel, there is a uniform decline in hem [more..]